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Comparative evaluation of multiomics integration tools for the study of prediabetes: insights into the earliest stages of type 2 diabetes mellitus
Type 2 diabetes mellitus (T2D) remains a critical health concern, particularly in its early disease stages such as prediabetes. Understanding these early stages is paramount for improving patient outcomes. Multiomics data integration tools offer promise in unraveling the underlying mechanisms of T2D. The advent of high-throughput technology and the increasing availability of multiomics data has led to the development of several statistical and network-based integration methods. However, the performance of such methods varies, requiring their output evaluation in an unbiased manner. Here, we
Smart Prediction of Circulatory Failure: Machine Learning for Early Detection of Patient Deterioration
Circulatory failure, also known as shock, is a critical condition that can have serious consequences for one's health. Early detection and timely intervention are crucial for improving patient outcomes. Machine learning (ML) models have shown promise in predicting circulatory failure based on clinical data. In our study, we examined different machine learning (ML) models to predict circulatory failure in patients who were admitted to the intensive care unit (ICU) with suspected circulatory problems. The ML model we developed used various algorithms like random forest, LG, XGB, Decision Tree
Hybrid Global Optimization Algorithm for Feature Selection
This paper proposes Parallelized Linear Time-Variant Acceleration Coefficients and Inertial Weight of Particle Swarm Optimization algorithm (PLTVACIW-PSO). Its designed has introduced the benefits of Parallel computing into the combined power of TVAC (Time-Variant Acceleration Coefficients) and IW (Inertial Weight). Proposed algorithm has been tested against linear, non-linear, traditional, and multiswarm based optimization algorithms. An experimental study is performed in two stages to assess the proposed PLTVACIW-PSO. Phase I uses 12 recognized Standard Benchmarks methods to evaluate the
Stem cell for PD: Technical considerations
The emergence of very sophisticated stem therapy or regenerative medicine can be attributed to the identification and extraction of pluripotent ESCs. This breakthrough resolved the ethical dilemma linked to embryonic stem cells and facilitated the initiation of clinical trials and subsequent rapid progress in the subsequent years. This chapter explores the prospect of stem cell therapy as a treatment for Parkinson's disease (PD), a degenerative neurological condition. The text commences by providing an overview of stem cells, clarifying their distinct regenerative characteristics and their
Malware Detection Techniques
Computers and systems are vulnerable to many threats. Security researchers identified the malware as the major computers and systems threat. Malware can be classified into different types depending on the infection, attacking target, and persistence technique. In this paper, Malware detection techniques are observed with the identification of each technique's strengths and weaknesses points, followed by a comparison between all malware detection techniques. © 2022 IEEE.
Correction to: Genomic landscape of hepatocellular carcinoma in Egyptian patients by whole exome sequencing (BMC Medical Genomics, (2024), 17, 1, (202), 10.1186/s12920-024-01965-w)
Tables 2, 3, and 6, as shown in the original publication, were modified to black and white during the typesetting process. Following the publication, the authors requested that the tables be reverted to their original-colored versions, as the colors in the heatmap indicate the number of pathogenic variants present in genes. Green indicates the smallest number, and red indicates the highest number. The colored tables are as follows: Heatmap for pathogenic variants in highly mutated genes in HCC samples Heatmap for pathogenic variants in highly mutated genes in Non-HCC samples Heatmap showing
Cross-Modality Deep Transfer Learning: Application to Liver Segmentation in CT and MRI
Liver diseases cause up to two million deaths yearly. Their diagnosis and treatment plans require an accurate assessment of the liver structure and tissue characteristics. Imaging modalities such as computed tomography (CT) and Magnetic resonance (MR) can be used to assess the liver. CT has better spatial resolution compared to MR, which has better tissue contrast. Each modality has its own applications. However, CT is widely used due its ease of access, lower cost and a shorter examination time. Liver segmentation is an important step that helps to accurately identify and isolate the liver
ArFakeDetect: A Deep Learning Approach for Detecting Fabricated Arabic Tweets on COVID-19 Vaccines
Social media platforms have emerged as major sources of false information, particularly regarding health topics. like COVID-19 vaccines. This rampant dissemination of inaccurate content contributes significantly to vaccine hesitancy and undermines vaccination campaigns. This research addresses the pressing need for automated methods to distinguish between factual and fabricated Arabic tweets concerning vaccines, aiming to mitigate the spread of misinformation on these platforms. The proposed approach utilizes deep learning techniques, leveraging pre-trained Arabic language models (Arabert)
Iterative Refinement Algorithm for Liver Segmentation Ground-Truth Generation Using Fine-Tuning Weak Labels for CT and Structural MRI
Medical image segmentation is indicated in a number of treatments and procedures, such as detecting pathological changes and organ resection. However, it is a time-consuming process when done manually. Automatic segmentation algorithms like deep learning methods overcome this hurdle, but they are data-hungry and require expert ground-truth annotations, which is a limitation, particularly in medical datasets. On the other hand, unannotated medical datasets are easier to come by and can be used in several methods to learn ground-truth masks. In this paper, we aim to utilize across-modalities
A Flow-Based Anomaly Detection Approach With Feature Selection Method Against DDoS Attacks in SDNs
Software Defined Networking (SDN) is an emerging network platform, which facilitates centralised network management. The SDN enables the network operators to manage the overall network consistently and holistically, regardless the complexity of infrastructure devices. The promising features of the SDN enhance network security and facilitate the implementation of threat detection systems through software applications using open APIs. However, the emerging technology creates new security concerns and new threats that do not exist in the current traditional networks. Distributed Denial of Service
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