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Tracking Antibiotic Resistance from the Environment to Human Health
Antimicrobial resistance (AMR) is one of the threats to our world according to the World Health Organization (WHO). Resistance is an evolutionary dynamic process where host-associated microbes have to adapt to their stressful environments. AMR could be classified according to the mechanism of resistance or the biome where resistance takes place. Antibiotics are one of the stresses that lead to resistance through antibiotic resistance genes (ARGs). The resistome could be defined as the collection of all ARGs in an organism’s genome or metagenome. Currently, there is a growing body of evidence
Introduction to genomics-based pharmaceutical applications
Biomedical research and pharmaceutical development have been profoundly impacted by genomics in recent years, with researchers gaining new understanding of the genetic pathways underlying disease and opening up new opportunities for the creation of targeted therapeutic interventions. Without a comprehensive grasp of the genetic mechanisms at play, medication discovery approaches in the past often relied on trial and error, targeting particular symptoms or pathways. However, the advent of genomics has changed the game. Scientific advances in high-throughput DNA sequencing have allowed
Intrusion Detection in VANETs and ACVs using Deep Learning
There are many novel techniques for intrusion detection in vehicular ad hoc networks and autonomous and connected vehicles. Detecting and reporting an attack is the main responsibility of an Intrusion detection system (IDS). Deep learning is used to make IDS smarter and more accurate. It implies other challenges on the other hand. This paper covers the proposed IDS based deep learning solutions and comparing effectiveness and efficiency of those solutions. © 2022 IEEE.
Using Blockchain Technology in MANETs Security
Many systems have recently begun to examine blockchain qualities in order to create cooperation enforcement methods. This paper provides a complete and extensive evaluation of work on multi-hop MANETs with blockchain-based trust control between nodes. We contextualize the snag of security in MANETs resulting from the lack of trust between the participating nodes. We present the blockchain concepts and discuss the limitation of the current blockchain in MANETs. We review the promising proposed ideas in the state-of-the-art based on research papers. Finally, we discuss and summarize strategies
Genomic landscape of hepatocellular carcinoma in Egyptian patients by whole exome sequencing
Background: Hepatocellular carcinoma (HCC) is the most common primary liver cancer. Chronic hepatitis and liver cirrhosis lead to accumulation of genetic alterations driving HCC pathogenesis. This study is designed to explore genomic landscape of HCC in Egyptian patients by whole exome sequencing. Methods: Whole exome sequencing using Ion Torrent was done on 13 HCC patients, who underwent surgical intervention (7 patients underwent living donor liver transplantation (LDLT) and 6 patients had surgical resection}. Results: Mutational signature was mostly S1, S5, S6, and S12 in HCC. Analysis of
Keyed Watermarks: A Fine-grained Tracking of Event-time in Apache Flink
Big Data Stream processing engines such as Apache Flink use windowing techniques to handle unbounded streams of events. Gathering all pertinent input within a window is crucial for event-time windowing since it affects how accurate results are. A significant part of this process is played by watermarks, which are unique timestamps that show the passage of events in time. However, the current watermark generation method in Apache Flink, which works at the level of the input stream, tends to favor faster sub-streams, resulting in dropped events from slower sub-streams. In our analysis, we found
Ad-hoc Networks Performance based on Routing Protocol Type
There are many situations where there is a need for certain devices to be connected in a network independently without having a heavy infrastructure or human interventions to configure and connect them. This type of network is called ad-hoc networks. The key concern with such networks is how nodes communicate with each other and exchange information efficiently and securely. The issue with ad hoc networks is that traditional routing protocols are not suitable for such networks. In this paper, the performance of specific routing protocols for ad hoc networks will be evaluated. © 2022 IEEE.
A Machine Learning-Based Intrusion Detection System for IoT Electric Vehicle Charging Stations (EVCSs)
The demand for electric vehicles (EVs) is growing rapidly. This requires an ecosystem that meets the user’s needs while preserving security. The rich data obtained from electric vehicle stations are powered by the Internet of Things (IoT) ecosystem. This is achieved through us of electric vehicle charging station management systems (EVCSMSs). However, the risks associated with cyber-attacks on IoT systems are also increasing at the same pace. To help in finding malicious traffic, intrusion detection systems (IDSs) play a vital role in traditional IT systems. This paper proposes a classifier
Generalisability of fetal ultrasound deep learning models to low-resource imaging settings in five African countries
Most artificial intelligence (AI) research and innovations have concentrated in high-income countries, where imaging data, IT infrastructures and clinical expertise are plentiful. However, slower progress has been made in limited-resource environments where medical imaging is needed. For example, in Sub-Saharan Africa, the rate of perinatal mortality is very high due to limited access to antenatal screening. In these countries, AI models could be implemented to help clinicians acquire fetal ultrasound planes for the diagnosis of fetal abnormalities. So far, deep learning models have been
Oral Dental Diagnosis Using Deep Learning Techniques: A Review
The purpose of this study is to investigate the gradual incorporation of deep learning in the dental healthcare system, offering an easy and efficient diagnosis. For that, an electronic search was conducted in the Institute of Electrical and Electronics Engineers (IEEE) Xplore, ScienceDirect, Journal of Dentistry, Health Informatics Journal, and other credible resources. The studies varied with their tools and techniques used for the diagnosis while coping with the rapid deep-learning evolving base, with different types of conducting tools and analysis for the data. An inclusion criterion was
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