Background: Remarkable work has been recently introduced to enhance the usage of Electromyography (EMG) signals in operating prosthetic arms. Despite the rapid advancements in this field, providing a reliable, naturalistic myoelectric prosthesis remains a significant challenge. Other challenges include the limited number of allowed movements, lack of simultaneous, continuous control and the high computational power that could be needed for accurate decoding. In this study, we propose an EMG-based multi-Kalman filter approach to decode arm kinematics; specifically, the elbow angle (θ), wrist

Background: The novel coronavirus (SARS-CoV-2) caused lethal infections worldwide during an unprecedented pandemic. Identification of the candidate viral epitopes is the first step in the design of vaccines against the viral infection. Several immunoinformatic approaches were employed to identify the SARS-CoV-2 epitopes that bind specifically with the major histocompatibility molecules class I (MHC-I). We utilized immunoinformatic tools to analyze the whole viral protein sequences, to identify the SARS-CoV-2 epitopes responsible for binding to the most frequent human leukocyte antigen (HLA)

Medicines based on messenger RNA (mRNA) hold immense potential, as evidenced by their rapid deployment as COVID-19 vaccines. However, worldwide distribution of mRNA molecules has been limited by their thermostability, which is fundamentally limited by the intrinsic instability of RNA molecules to a chemical degradation reaction called in-line hydrolysis. Predicting the degradation of an RNA molecule is a key task in designing more stable RNA-based therapeutics. Here, we describe a crowdsourced machine learning competition (‘Stanford OpenVaccine’) on Kaggle, involving single-nucleotide

Since its emergence as a pandemic in March 2020, coronavirus disease (COVID-19) outcome has been explored via several predictive models, using specific clinical or biochemical parameters. In the current study, we developed an integrative non-linear predictive model of COVID-19 outcome, using clinical, biochemical, immunological, and radiological data of patients with different disease severities. Initially, the immunological signature of the disease was investigated through transcriptomics analysis of nasopharyngeal swab samples of patients with different COVID-19 severity versus control

Combinations of direct-acting antivirals are needed to minimize drug resistance mutations and stably suppress replication of RNA viruses. Currently, there are limited therapeutic options against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and testing of a number of drug regimens has led to conflicting results. Here, we show that cobicistat, which is an FDA-approved drug booster that blocks the activity of the drug-metabolizing proteins cytochrome P450-3As (CYP3As) and P-glycoprotein (P-gp), inhibits SARS-CoV-2 replication. Two independent cell-to-cell membrane fusion

This paper describes our submission UFAL MULTIVEC to the WMT16 Quality Estimation Shared Task, for English- German sentence-level post-editing effort prediction and ranking. Our approach exploits the power of bilingual distributed representations, word alignments and also manual post-edits to boost the performance of the baseline QuEst++ set of features. Our model outperforms the baseline, as well as the winning system in WMT15, Referential Translation Machines (RTM), in both scoring and ranking sub-tasks. © 2016 Association for Computational Linguistics.

This paper introduces a proposed fabric defect detection technique based on additive wavelet transform. In this paper, à trous wavelet is utilized to extract the approximate sub image at an appropriate level. The objective of the proposed technique is to enhance energy of defective region and attenuate energy of background in the selected level. An improved thresholding method based on statistical calculation is used. © 2020, Menoufia University, Faculty of Electronic Engineering. All rights reserved.

The internet of things (IoT) has provided a promising opportunity to build powerful systems and applications. Security is the main concern in IoT applications due to the privacy of exchanged data using limited resources of IoT devices (sensors/actuators). In this paper, we present a classification of IoT modes of operation based on the distribution of IoT devices, connectivity to the internet, and the typical field of application. It has been found that the majority of IoT services can be classified into one of four IoT modes: Gateway, device to device, collaborative, and centralized. The

In the field of pattern recognition multiple classifier systems based on the combination of outputs from different classifiers have been proposed as a method of high performance classification systems. The objective of this work is to develop a fuzzy Gaussian classifier for combining multiple learners, we use a fuzzy Gaussian model to combine the outputs obtained from K-nearest neighbor classifier (KNN), Fuzzy K-nearest neighbor classifier and Multi-layer Perceptron (MLP) and then compare the results with Fuzzy Integral, Decision Templates, Weighted Majority, Majority Naïve Bayes, Maximum

For the past decade, Internet of Things (IoT) had an important role in our lives. It connects a large number of embedded devices. These devices fulfill very difficult and complicated tasks, which facilitate our work. Till now the security of IoT faces many challenges such as privacy, authentication, confidentiality, trust, middleware security, mobile security and policy enforcement. In order to provide a secure environment for IoT, this paper proposes a framework for IoT devices. © 2017 IEEE.